Project: The role of pre-mRNA structures in the regulation of splicing
Research group: Folk
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Deadline is closed
The Faculty of Science, Charles University (Prague, Czechia) invites applications for a Post-doctoral position in the Biology Section for the project realized in the OP RDE, Call No. 02_18_053 “International mobility of research, technical and administrative workers of research organizations”.
The position is available to study the roles of pre-mRNA structures in the regulation of splicing in the laboratory of dr. Petr Folk. Regulatory roles of intron-harbored structures were established for several genes of S. cerevisiae, e.g., RPS9, RPS14, RPL22, or RPL30, but the detailed mechanisms whereby they affect splicing remains to be elucidated. The project will focus on the characterization of RNA structures and RNA-protein interactions in the context of splice-site recognition. The candidate should be interested in areas of RNA biochemistry/ biology. Because of the limited time of the project (13 months), previous experience with nucleic acid techniques such as chemical probing methods, methods to study protein-RNA interactions, fluorescence spectroscopy or TIRF microscopy will be an advantage.
Eligibility criteria:
Selection process:
Selection will be based on the relevance of candidate’s professional interests and experience, excellence in research achievements.
Position duration, starting date and remuneration:
The position duration is 13 months, starting on January 1, 2021 and ending on January 31, 2022. The gross monthly salary is 62 237 CZK (approx. 2 468 EUR) including health insurance and social insurance coverage. The job status is full-time - 40 hours per week.
Required application materials:
How to submit application materials:
Please send email with the required application materials to the project coordinator, Mr. Miroslav Kotrc: miroslav.kotrc@natur.cuni.cz. For more information related to the project, contact Dr. Petr Folk: folk@natur.cuni.cz.
Deadline is closed